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ULTOMIRIS requires dilution to a final concentration of 5 mg/mL. Use aseptic technique to prepare ULTOMIRIS as follows: 1. The number of vials to be diluted is determined based on the individual patient’s weight and the prescribed dose [see Dosage and Administration (2.2)]. 2. Prior to dilution, visually inspect the solution in the vials; the ...

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0 to 1 dose → This is a new request OR the patient has received only 1 dose. Skip to Clinical Criteria Questions E. Has the patient experienced an adverse event with the requested product that has not responded to conventional interventions (eg acetaminophen, steroids, diphenhydramine, fluids or other pre-medications) or a severe adverse

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Jul 01, 2019 · Recommended Dosage Regimen – aHUS. For patients 18 years of age and older, Soliris therapy consists of: 900 mg weekly for the first 4 weeks, followed by; 1200 mg for the fifth dose 1 week later, then; 1200 mg every 2 weeks thereafter.

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3 Institute of Clinical Medicine, Campus Ahus, University of Oslo, Norway; HØKH, Research Centre, Akershus University Hospital, Norway. 4 Diakonhjemmet Hospital, Department of Geriatric Psychiatry, Pastor Fangens vei 18, 0854 Oslo, Norway. 5 Department of Research and Development in Mental Health, Akershus University Hospital, Norway. Feb 04, 2019 · And then second, as we look to model Ultomiris in aHUS, it looks like based on the dosing difference that there's -- there will be a 40% average price discount for Ultomiris in aHUS versus Soliris ...

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Ultomiris has a list price of $6,404 per vial, compared with $6,543 per vial for Soliris, which accounts for more than 80% of Alexion’s total sales. On average, the annual cost for Ultomiris maintenance doses is about $458,000, a discount of about 33% to the labeled maintenance dose of Soliris in aHUS, Alexion noted.

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Jun 24, 2019 · → Kymab has agreed to put its plat­form tech to use for the UK med­ical char­i­ty LifeArc, gain­ing a new in­vestor who’s tak­ing a $30 mil­lion eq­ui­ty stake in the biotech.

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